MENSTRUAL CYCLE

  • The regularly recurring physiologic changes in the endometrium that culminate in its shedding ( "menstruation" MENSTRUATION). Menstrual cycles vary in length; the average is about 28 days.
  • The menstrual flow generally lasts about 5 days, although this too varies from person to person. Women menstruate from puberty to menopause, except during pregnancy. During the first 14 days of the 28-day menstrual cycle, a follicle containing an ovum develops in the ovaries.
  • As the menstrual flow ceases, the lining of the uterus is stimulated by estrogen and begins to increase in thickness to prepare for reproduction. On about the fourteenth day of the cycle, "ovulation" OVULATION takes place and the ovary discharges the ovum.
  • The ruptured follicle is transformed into a yellowish material called the corpus luteum, which in turn secretes progesterone. Progesterone acts on the endometrium, building up tissues with an enriched supply of blood to nourish the future embryo.
  • If conception does not take place, the estrogen level in the blood falls, the endometrium is no longer stimulated, and the uterus again becomes thinner. Blood circulation slows, blood vessels contract, and the unused tissue breaks down into the bloody discharge known as menstruation.

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